Parasites on animals include fleas, ticks, lice, hairy cysts, iris-sucking nematodes, roundworms, cestodes, hookworms, pinworms, whipworms, coccidia, heartworm, trichinella, toxoplasma, scabies mites, helminths, face-huggers, oriental hairy round and rabbit cocktail nematodes, cryptogramma, oral filarial worms, wheel worms, ichthyosaur, Chinese lernae, oblique tubeworm, coccidiosis, cucumber worm, tongue cup worm, straw worm, anchor head lernae, iodosporidium, mucosporidium, dactyloidiasis, hookworm larvae, blood-dwelling trematode, trigonid, nine-river head groove tapeworm, tongue tapeworm, amoeba, echinococcus, capillary nematode, fish monster worm, etc.

From the entry of parasites into animals, the establishment of parasitic relationships, the development of parasitic diseases, and the control and termination of parasitic epidemics are areas that scientists have elucidated with theory or from theory to practice.

Ace Therapeutics provides multi-omics services for animal parasites, including but not limited to genomics, epigenomics, transcriptomics, proteomics, metabolomics, single-cell omics, and spatial omics. Each step from sample extraction, library construction, sequencing/assay to data analysis is scientifically and meticulously designed.

Multi-Omics Service Options for Animal Parasites

1. Single-cell omics

We provide single-cell histology services for animal parasites, including single-cell genome sequencing, single-cell exome sequencing, single-cell transcriptome sequencing, single-cell whole-transcriptome sequencing, single-cell whole-genome methylation sequencing, and single-cell genome and transcriptome parallel sequencing (G&T Seq). We can apply these technologies for unbiased, high-throughput, and high-resolution analysis of individual cells of animal parasites. We can realize detailed studies on cell composition, identify cell subpopulations, discover rare cells, and analyze transcriptional dynamic changes and gene regulatory relationships of animal parasites. And provide a theoretical basis for revealing the developmental trajectories and pathogenic mechanisms of animal parasites.

2. Transcriptomics

We provide transcriptome sequencing and analysis services for animal parasites, including scRNA-seq, spatial transcriptome sequencing, mRNA-seq, lncRNA-seq, circRNA-seq, small RNA-seq, whole transcriptome sequencing, and comparative transcriptome sequencing. In addition, we can provide multi-omics integration analysis. We help you study the gene composition and characteristics, transcription, and regulation among genes of animal parasites under different conditions, and achieve efficient mining of functional genes. To provide insight into the origin, evolution, and pathogenesis of animal parasites, as well as to provide new ideas for diagnosis, new drug design, and vaccine development. For example, transcriptomic services for ascarid, tapeworms, hookworms, pinworms, Giardia lamblia, Endolymphatic amoebae, schistosome, toxoplasma, Wuchereria bancrofti, Sarcoptes scabiei, flea and tick.

3. Metabolomics and proteomics

We offer metabolomics and proteomics services for animal parasites, including targeted, untargeted metabolomics iTRAQ/TMT labeled quantitative proteomics, label-free quantitative proteomics, DIA quantitative proteomics, qualitative identification proteomics, and qualitative modification proteomics. We can help you to carefully analyze the metabolite/protein composition and changes of such parasites before and after parasitic activity, as well as biological issues such as nutrient acquisition, toxin production and virulence, and pathogenicity. This can provide new ideas for animal parasite growth and development, environmental adaptation, parasite-host interactions, molecular markers, new drug design, and vaccine development, etc.

4. Epigenomics

We offer epigenomics services for animal parasites, including but not limited to ChlP-seq, RIP-seq, and ATAC-seq. We can help you analyze the expression level changes of non-genetic sequences and chromatin conformation changes in animals before/during/after parasitization, and provide a basis for a detailed study of the molecular mechanisms in the biological processes of cell differentiation, reproduction, and pathogenesis of animal parasites, and for finding the key molecules that block the development/reproduction/pathogenesis of parasites, to help the research and development of antiparasitic drugs and vaccine development.

Service Details

• Sample type: in most cases, samples are taken in biological processes/gradients such as the origin, infection, development, pathogenesis, treatment of animal parasites, or the type of sample chosen according to the purpose of your study.
• Delivery content: experiment report.
• Service fee: please get it through online inquiry.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service