Pinworms are common human parasites that cause pinworm disease. Pinworms are the most widespread of all worms, with approximately 210 million people worldwide infected with pinworms. Adult females can grow to 8-13 mm and are found in the human intestine, mainly in the lower ileum, cecum, and colon; in severe cases of pinworm infection, they can travel up into the stomach and esophagus. During the host's sleep, female pinworms travel outside the anus and lay eggs in the perianal and perineal skin folds of the host. Unlike most parasites, however, pinworms do not enter the bloodstream and cannot survive in other parts of the body. The clinical manifestations of pinworm disease include itching, gastrointestinal symptoms, inflammation, psychiatric symptoms and ectopic parasitism.

The study of the transcriptional regulation pattern of pinworms by high-throughput transcriptome level sequencing and analysis provides new ideas for the interaction between mRNA, circRNA, lincRNA, microRNA and other small molecules and related systemic mechanisms, and provides a reference for the research related to pinworm diseases.

Ace Therapeutics provides transcriptome level sequencing and analysis services for pinworms, aiming to facilitate gene expression abundance detection, structural analysis, functional gene mining, and gene regulation mechanism research in pinworms, and to provide a theoretical basis for a comprehensive study of gene regulation, expression patterns, and their interaction with the host during pinworm development and reproduction.

Transcriptome Sequencing Service Options for Pinworms

• Transcriptome sequencing service for pinworm without reference genome
• Transcriptome sequencing service for pinworm with reference genome

The transcriptome sequencing can quantify the mRNA produced by certain state of pinworms, detect the difference of gene expression level, and also realize the structural analysis, also can discover the rare transcripts, accurately identify the variable shear sites, gene fusion, etc., and does not depend on the reference genome.

• Full-length transcriptome sequencing service for pinworm

We also provide full-length transcriptome sequencing and analysis services for pinworm. This technical service can directly obtain the full-length transcript information without assembly, which can guarantee the accuracy of transcriptome sequencing results to a greater extent. For pinworms without reference sequences, full-length transcriptome sequencing can construct a high-quality gene set and lay the foundation for subsequent functional studies of pinworms. For pinworms with reference sequences, new transcripts can be discovered to improve the reference gene set; and structural variants such as variable splicing and gene fusion can be identified.

• mRNA sequencing service for pinworm
• LncRNA sequencing service for pinworm
• CircRNA sequencing service for pinworm
• Whole transcriptome sequencing service for pinworm

The sequencing of large RNAs of mRNA, lncRNA, and circRNA of pinworms will provide rapid, comprehensive, and accurate information on all large RNA transcript data related to specific biological processes (e.g., development, disease) for the study of cell differentiation/development and regulatory mechanisms of pinworms, the search for disease markers, molecular diagnosis of diseases, and the development of gene drugs.

• Small RNA sequencing service for pinworm

Small RNA sequencing of pinworms can achieve the identification of small RNA sequences, target gene analysis and functional analysis, as well as the analysis of multiple small RNA types including miRNA, siRNA, piRNA and other research needs. It is important for pinworm growth and development regulation research, pinworm disease occurrence regulation mechanism, searching for biomarkers, target drug research, etc.

Service Details

Sample requirements: each service is with independent sample requirements, please consult our technical engineers or sales staff for details.
Delivery content: experiment report.
Test fee: please get it through online inquiry.

Service Flow

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service