Entamoeba histolytica generally co-habits in the host colon, only under certain conditions invades the intestinal wall or is carried by the bloodstream to other organs and causes causes amoebic dysentery and various types of amoebiasis, for a global distribution. Its intermediate hosts are mainly humans, cats, dogs and rats. Currently, studies have demonstrated that the pathogenic mechanism of Entamoeba histolytica is complex, involving various factors such as the pathogenicity of the strain, the parasitic environment and the immune status of the host. Amoeba trophozoites have the ability to invade host tissues or organs, adapt to the host's immune response and express pathogenic factors. Its trophozoites express pathogenic factors that destroy extracellular mesenchyme, contact-dependent lysis of host tissues and resistance to lysis by complement, where destruction of extracellular mesenchyme and lysis of host tissues are important modes of worm invasion.

The transcriptomic study of Entamoeba histolytica provides new ideas for the systematic study of the interactions between genes, RNAs, proteins and other small molecules and related systemic mechanisms, and also provides a reference for the related studies of amoebiasis.

Ace Therapeutics provides transcriptome sequencing and analysis services for Entamoeba histolytica, providing a theoretical basis to reveal the regulatory mechanisms during the developmental reproduction of Entamoeba histolytica and the mechanism of insect-host interactions.

Service Options for Entamoeba histolytica Transcriptome Sequencing

We offer transcriptome sequencing services for Entamoeba histolytica, including but not limited to the following, which you can choose flexibly according to your needs.

• Dual RNA sequencing service for Entamoeba histolytica and host

We provide Dual RNA-seq service for research between Entamoeba histolytica and host. Dual RNA-seq can reveal the gene expression dynamics and regulatory relationships between Entamoeba histolytica and host, and obtain the mechanism of interaction between the two species.

• Transcriptome sequencing service for Entamoeba histolytica (with/without reference genome)
• Full-length transcriptome sequencing service for Entamoeba histolytica

We provide transcriptome sequencing and third-generation full-length transcriptome sequencing and analysis services for Entamoeba histolytica (with/without reference genome). For quantifying changes in the expression levels of each transcript during its growth and under different conditions, enabling gene annotation, differential gene expression and alternative splicing. We also provide mRNA, lncRNA, circRNA, small RNA and whole transcriptome sequencing and analysis services for Entamoeba histolytica. It is used to analyze the regulatory effects of each RNA on the transcriptional and post-transcriptional levels of mRNAs, to construct regulatory networks of various RNAs, and to analyze their regulatory mechanisms at a deeper level. It provides an important theoretical basis for the discovery of new drug targets and the development of potent drugs.

Service Details

Sample requirements: each service is with independent sample requirements, please consult our technical engineers or sales staff for details.
Delivery content: experiment report.
Test fee: please get it through online inquiry.

Service Flow

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service