The scabies mite belongs to the family Sarcoptidae, the Acaridea, and is a permanent parasitic mite. As soon as a person touches it, it becomes parasitic in the epidermis of human and mammalian skin, causing severe itching and causing skin lesions such as papule, pustule, nodule, plaque, or blister (vesicle or bulla), which is known as scabies. The majority of scabies mites are tiny and cannot be cultured, and it is difficult to obtain the source of the mites, so there is less research. Most of the mites reported by transcriptome sequencing are mainly agricultural mites, including leaf mites, phytoseiid mites, root mites, siderophores, and tile mites. The only medical mites that are closely related to human and animal health are rabbit itch mite, carrion mite, canine mange mite, dust mite, and chicken skin spider mite.

The transcriptome not only enables rapid access to a large amount of genetic data (mRNA, rRNA, tRNA and other non-coding RNAs) for transcript structure, variation and functional studies of non-coding regions, which lays a solid molecular foundation for the study of genes related to mite drug resistance, growth and development and pathogenesis, and other related functions.

Ace Therapeutics provides transcriptome sequencing and analysis services for Sarcoptes scabiei, aiming to contribute to the study of gene expression abundance detection and structural analysis, functional gene mining, and gene regulation mechanism research of Sarcoptes scabiei, to promote more in-depth gene expression research, and to provide more valuable information for the molecular mechanism of Sarcoptes scabiei-host interaction and the development of anti-Sarcoptes scabiei drugs for animals.

Transcriptome Sequencing Service Options for Sarcoptes scabiei

• Transcriptome sequencing service for Sarcoptes scabiei without reference genome
• Transcriptome sequencing service for Sarcoptes scabiei with reference genome
• Full-length transcriptome sequencing service for Sarcoptes scabiei

We used high-throughput sequencing technology for cDNA sequencing of Sarcoptes scabieis to obtain transcripts relatively quickly. Moreover, the transcriptomes of scabies mites with/without genomic data can be effectively annotated to discover unknown or low-abundance transcripts, and more importantly, to reveal the changes in gene expression of scabies mites under different conditions.

We also provide full-length transcriptome sequencing and analysis services for Sarcoptes scabiei. It can directly obtain the full-length sequence of mRNA, which can more accurately decipher the structural information of mRNA, overcome the problem of short splicing and incomplete information of transcripts of species without reference genome, obtain full-length mRNA sequence, realize homologous isoform analysis, single base variation detection, variable splicing analysis, homologous gene identification and allele identification of Sarcoptes scabiei.

• Small RNA sequencing service for Sarcoptes scabiei
• LncRNA sequencing service for Sarcoptes scabiei
• CircRNA sequencing service for Sarcoptes scabiei
• Whole transcriptome sequencing service for Sarcoptes scabiei

We can analyze mRNA, lncRNA, circRNA, microRNA of scabies alone, or combine multiple RNAs and endogenous competitive RNA integration analysis to explore the potential regulatory network mechanism, reveal transcriptional regulation, and carefully study its developmental evolution, immune mechanism, pathogenesis and drug targets.

Service Details

Sample requirements: each service is with independent sample requirements, please consult our technical engineers or sales staff for details.
Delivery content: experiment report.
Test fee: please get it through online inquiry.

Service Flow

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service