Giardia lamblia, a mild intestinal disease caused by Giardia protozoa, is one of the ten major parasitic diseases endangering human health worldwide. In particular, Giardia causes fatal diarrhea in AIDS patients and has attracted the attention of the medical community. The mechanism of pathogenesis is not fully understood and is related to various factors such as strain virulence, organism response and symbiotic internal environment.

The sequencing and analysis of Giardia lamblia at the transcriptome level will screen for transcriptional regulation-related genes and further explore their gene transcriptional regulation mechanisms, which will lay the foundation for the study of the immune evasion mechanism of Giardia lamblia in the host from the molecular level. It is also important for the study of giardia gene expression regulation mode as well as the formulation of parasitic disease control measures and the development research of AIDS lethal diarrhea drugs.

Ace Therapeutics provides transcriptome sequencing and analysis services for Giardia lamblia, aiming to facilitate efficient elucidation of regulatory networks at the transcriptional level, in order to study the molecular biology of Giardia lamblia at the level of transcriptional regulation, gaining a more comprehensive understanding of transcriptional regulatory mechanisms, and providing an important theoretical basis for the discovery of new drug targets and the development of specific drugs.

Transcriptome Sequencing Service Options for Giardia lamblia

We offer transcriptome sequencing services for Giardia lamblia, including but not limited to the following, which you can choose flexibly according to your needs.

• Transcriptome sequencing service for Giardia lamblia with/without reference genome
• Third-generation full-length transcriptome sequencing and analysis services for Giardia lamblia with/without reference genome

The next and third generation transcriptome sequencing of Giardia lamblia can quantify the changes in the expression level of each transcript during its growth and under different conditions. The main purpose is to achieve gene annotation and screening of Giardia lamblia and to improve its genome annotation; to achieve differential gene expression and variable shear event changes; to achieve post-transcriptional regulatory mechanism studies, fusion gene studies and more accurate quantitative analysis.

• mRNA sequencing service for Giardia lamblia
• LncRNA sequencing service for Giardia lamblia
• CircRNA sequencing service for Giardia lamblia
• Small RNA sequencing service for Giardia lamblia
• Whole transcriptome sequencing service for Giardia lamblia

We provide mRNA, lncRNA, circRNA, small RNA and whole transcriptome sequencing and analysis services for Giardia lamblia. By sequencing and analysis of mRNA, lncRNA, circRNA, and small RNA, we analyze the regulatory effects of each RNA on the transcriptional and post-transcriptional levels of mRNA. Construct ceRNA regulatory network by whole transcriptome analysis of lncRNA, circRNA, mRNA and miRNA of Giardia lamblia, and dig into gene function and analyze its regulatory mechanism at a deeper level. It provides an important theoretical basis for the discovery of new drug targets and the development of specific drugs.

• Dual RNA sequencing service for Giardia lamblia and host

We provide sequencing and analysis services for the transcriptome of Giardia lamblia-host interactions. We can capture the transcripts of Giardia lamblia-host interactions by high-throughput sequencing, dissect the dynamic changes of gene expression, construct interaction networks, and screen for active functional genes. We can also provide advanced analyses such as WGCNA, virulence factor annotation or temporal analysis for different research purposes. It is mainly used for in-depth study of physiological adaptation and molecular response mechanism, Giardia lamblia-host immunity, Giardia lamblia-host symbiosis mechanism, etc.

Service Details

Sample requirements: each service is with independent sample requirements, please consult our technical engineers or sales staff for details.
Delivery content: experiment report.
Test fee: please get it through online inquiry.

Service Flow

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service