Ectoparasites are mainly insects, such as mosquitoes, lacewings, lice, fleas, and ticks. When they sting and suck blood when they come into contact with the host body surface, sucking blood or sucking organic material on the host body for nutrition and then leaving. Ectoparasites can also be called a temporary parasites. These ectoparasites are numerous in birds and mammals, and they not only suck the body fluids of the host directly but also transmit diseases. A variety of diseases (bacteria, viruses, parasites) are transmitted mainly through various transmission routes such as mechanical, biological, and genetic transmission.
More and more research is focused on ectoparasites, meticulously studying pathogenesis, anthelmintic drugs, and vaccine development. Ace Therapeutics is a specialist in the field of parasites, providing multi-omics services for ectoparasites, including but not limited to genomics, epigenomics, transcriptomics, proteomics, and metabolomics. The aim is to resolve the biological aspects of ectoparasites at the molecular level. Every step from sample extraction, and library sequencing, to data analysis, has been scientifically and meticulously designed to guarantee high-quality research results.
1. Transcriptomics
We provide ectoparasites transcriptomics services to our global clients based on our large-scale high-throughput transcriptome sequencing and screening technology platform. These include scRNA-seq, spatial transcriptome sequencing, mRNA-seq, lncRNA-seq, circRNA-seq, small RNA-seq, whole transcriptome sequencing, and comparative transcriptome sequencing. In addition to the standard transcriptome analysis, advanced analyses such as WGCNA, virulence factor annotation, and protein interaction networks are configured for different needs. This provides the basis for a comprehensive understanding of gene regulation, expression patterns, and parasite-host interactions during the complete/incomplete development and reproduction of in vitro parasites. For example, transcriptomics services for scabies, fleas, and tick.
2. Epigenomics
We provide epigenomics services for ectoparasites, including single-cell ATAC-seq, ATAC-seq, ChlP-seq, RIP-seq, and MeRlP-seq. We mainly analyze changes in gene expression levels based on non-genetic sequence alterations, such as DNA methylation and chromatin conformational changes. In-depth studies of important biological processes such as gene regulatory networks, developmental trajectories, and disease onset in ectoparasites reveal epigenetic differences and dynamic changes.
Ace Therapeutics is a contract service provider focused on parasitology research, providing innovative solutions and technologies for parasite detection, genetic engineering, and drug development. We support global research institutes, universities, and pharmaceutical companies in advancing their research goals.