Parasites are organisms that parasitize in or on the surface of a host (host) and derive nutrition from it. They can cause a variety of diseases, such as malaria, schistosomiasis, and cysticercosis. Therefore, parasite pathological techniques are widely used for the diagnosis and treatment of parasitic diseases and to support the study of the ecology, biology, and evolution of parasites. Modern parasitic pathology techniques have developed into a complex field that includes multiple aspects of molecular biology, immunology, microscopic examination, tissue sectioning, culture, and animal models. The development of these techniques has led to more accurate and effective diagnosis and treatment of parasites, as well as a better understanding of parasites.

Options for Technical Pathology Services for Parasite Research

As a company specializing in biotechnology services, Ace Therapeutics offers a comprehensive range of technical services in parasitic pathology. Our team consists of several experienced scientists with deep expertise and practical experience. We are committed to providing high-quality, reliable services to meet our client’s needs in parasitic pathology technology. We offer a variety of parasite pathology technical services, including but not limited to the following:

• Parasitic tissue sectioning and staining services

We can provide routine histology, special staining (e.g. silver staining), and immunohistochemical staining of parasite-infected tissues to observe the morphology, number, distribution, and extent of parasites affecting the tissues.

These services can help researchers gain insight into the pathological changes caused by the parasite, including inflammatory responses, apoptosis, necrosis, and proliferation at the site of infection, as well as evaluate the efficacy of new drugs, vaccines, and other treatments. Through histopathological examination, researchers can better understand the nature of parasite-host interactions and provide strong support for further exploration of strategies to treat parasitic infections.

• Microscopic examination services

We can observe the morphology and number of parasites through microscopy, including direct fluorescence microscopy, transmission electron microscopy, etc.

• Immunohistochemistry (IHC) service for parasites

Antibody validation service: We use techniques such as Western blot to validate the specificity and sensitivity of antibodies.

Specimen preparation service: We prepare tissue section samples for IHC staining using techniques such as conventional paraffin embedding or frozen sectioning.

Optimization of test conditions: Such as antibody concentration, buffer formulation, and incubation time to obtain the optimal immunoreactive signal and background noise.

Immunohistochemical staining service: We use techniques such as immunofluorescence staining or enzyme-labeled staining to detect the distribution and expression of parasite-specific antigens or proteins in tissue sections.

Data analysis and interpretation service: We provide IHC image acquisition, analysis, and interpretation to provide our clients with scientifically accurate data results and reports.

• In situ hybridization (ISH) service for parasites

Sample preparation: Collection and processing of parasite samples, including fixation, dewaxing, and sectioning steps to ensure the structural integrity and stability of the parasite.

Probe design and synthesis: Design and synthesize appropriate nucleic acid probes for use in ISH experiments according to customer needs and research objectives.

Parasite sample in situ hybridization (ISH) experiments: Use the above-prepared samples and probes to perform ISH experiments so that the probes interact with and signal parasite RNA or DNA, and observe the results under a microscope.

Data analysis and image processing: The obtained ISH results are subjected to data analysis and image processing to quantify the expression level and spatial distribution of the parasite RNA or DNA, and provide a reference basis for researchers.

It can help researchers to understand the expression pattern and spatial distribution of parasite RNA or DNA, and provide important support for the study of parasite infection and its treatment.

• Other customized services

We provide customized technical services in parasite pathology, such as the detection and identification of specific parasites, drug screening and evaluation, and toxicological evaluation, according to the needs and research purposes of our clients.

Ace Therapeutics provides comprehensive, efficient, and reliable technical services in parasitic pathology to meet the needs of our clients in the field of research. If you have any related needs, please feel free to consult us, we will be happy to provide you with professional services and technical support.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service