Opportunistic pathogenic parasitic infections have become one of the leading causes of death in patients with immunodeficiencies such as AIDS. Other opportunistic parasitic infections such as toxoplasma encephalitis and diarrhea caused by Cryptosporidium / Giardia lamblia / Strongyloides stercoralis are also very serious in immunodeficient patients. Currently, the biology of opportunistic parasites is poorly understood, with few studies on species identification, population infection status, and source/mode of infection, and most studies on opportunistic parasites lack animal models. The complex clinical manifestations of opportunistic parasitic diseases and the lack of sensitive and specific detection methods/therapeutic drugs are bottlenecks in the prevention and treatment of infectious diseases. The support of extensive basic research and the discovery of target molecules for diagnosis and treatment are the keys to solving these problems.

Ace Therapeutics provides multi-omics services for opportunistic parasites, including but not limited to genomics, epigenomics, transcriptomics, proteomics, and metabolomics. The aim is to explore the biology of opportunistic parasites at the molecular level to help find specific assays and develop specific drugs.

Multi-Omics Service Options for Opportunistic Parasites

1. Genomics

We provide genome sequencing services for opportunistic parasites, including next and third-generation library building and sequencing, and comparative genome sequencing. We aim to detect all the variants contained in DNA on a genome-wide scale to provide accurate guidance for the treatment of opportunistic pathogenic parasitic diseases such as Toxoplasma gondii encephalitis, Cryptosporidium carinii pneumonia, and Cryptosporidium diarrhea, and to provide a theoretical basis for accurate and rational preventive interventions, diagnosis and treatment, medication guidance, and health management.

2. Transcriptomics

We provide transcriptomics sequencing and analysis services for opportunistic parasites, involving scRNA-seq, spatial transcriptome sequencing, mRNA-seq, lncRNA-seq, circRNA-seq, small RNA-seq, whole transcriptome sequencing, and comparative transcriptome sequencing. Also, we can provide an integrated analysis of multiple omics. Gene function and gene structure are studied at a holistic level to provide a theoretical basis for biological processes such as growth and development, environmental adaptation, immune interactions, mutant phenotypes, and molecular marker development in opportunistic parasites.

3. Metabolomics

We offer metabolomics services for opportunistic parasites, including targeted and non-directed metabolomics techniques. We can help you to carefully analyze the composition and changes in metabolites of opportunistic parasites under different conditions, as well as biological aspects such as toxins and pathogenicity.

Service Details

• Sample type: in most cases, the samples are in the biological process /gradient of origin, infection, development, pathogenesis, treatment, etc. of the opportunistic parasites, or the sample type is selected according to the purpose of your study.
• Delivery content: experiment report.
• Service fee: please get it through online inquiry.

Our Advantages

• We have a dedicated parasitology technology platform, professional technicians, and scientific management systems to ensure the successful completion of your relevant parasite studies.
• We also provide other omics services for opportunistic parasites, such as epigenomics, metabolomics, single-cell omics, spatial omics, etc.
• We can also provide integrated multi-omics analysis for you to jointly interpret scientific questions at the multi-level molecular level, making the results more reliable and data-rich.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service