Product Type
Monoclonal antibody
Antibody
Cryptosporidium parvum Mouse anti-Protozoa Monoclonal (FITC) (BEL 0126) Antibody
Format
FITC-conjugated, unmodified
Description
This is an FITC-conjugated mouse monoclonal antibody to protozoa Cryptosporidium parvum. Validated for Flow and IF.
Target
Protozoa Cryptosporidium parvum
Host
Mouse
Reactivity
Protozoa (tested or 100% immunogen sequence identity)
Clonality
IgG3 Monoclonal
Clone
BEL 0126
Conjugations
FITC
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Purified oocysts from bovine feces.
Specificity
0126 recognizes a membrane antigen expressed by the oocysts of Cryptosporidium sp., an obligate enteric coccidian parasite of the phylum Apicomplexa that infects the gastrointestinal tract. The parasite is one of the most important enteric pathogens in both humans and animals. Since its first diagnosis in 1975, Cryptosporidiosis, has become one of the most prominent public health concerns worldwide. Cryptosporidium oocysts are resistant to chlorine and their small size makes removal by filtration difficult. Alternative methods have been developed such as UV and ozone treatment alongside monitoring using Immunofluorescence screening. Cryptosporidiosis is a disease affecting the intestines of mammals which is spread through the fecal-oral route. The main symptom of is self-limiting diarrhea in people with intact immune systems. However, in immunocompromised individuals, such as AIDS patients, infection can cause permanent & life-threatening diarrhea.
Applications
IF, Flo
Usage
Flow cytometry: use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% sodium azide, 1% BSA.
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
