Canine malarial worms are filarial worms that live in the right ventricle and pulmonary artery of dogs, also known as heartworms. Males are approximately 16 cm long and females are approximately 28 cm long and are white thread-like. Adult females produce embryonic microfilariae after mating with males in the ventricle. The canine larvae flow with the blood to the subcutaneous, when the mosquito or flea bite to suck blood into the insect body to develop, and finally reach the salivary glands and mouthparts. When mosquitoes and fleas bite other dogs, the microfilariae escape and burrow into the human subcutaneous, intermuscular and fatty tissues to develop and grow, and then migrate through the veins into the right ventricle and grow to maturity. As the adult worms live in the heart, they cause heart damage and gradually affect the health of dogs, cats and humans. Infection is followed by symptoms such as exercise intolerance, coughing and shortness of breath. In later stages, heart and lung failure, anemia, pulmonary effusion, ascites, jaundice, and death from liver and kidney failure occur.

Ace Therapeutics, as a service provider for parasite-related research, is focused on leveraging omics high-throughput technologies to advance basic research and the pharmaceutical industry. We can provide genome-level sequencing and analysis services for heartworm, laying the foundation for in-depth elucidation of mechanistic studies.

Genome Sequencing Service Options for Heartworm

We have a technical team with extensive experience in omics and can currently implement a variety of services for sequencing and analysis at the genomic level, as listed below. Upon completion of the service, we will deliver a detailed report to you. If you want to know more, you are welcome to consult us.

• Whole genome sequencing (Next / third generation) service for heartworm
• Whole genome resequencing service for heartworm
• Exome capture sequencing service for heartworm
• Target sequence capture sequencing service for heartworm
• Genome de novo sequencing service for heartworm
• Genome-wide association analysis services (GWAS) for heartworm
• Simplified genomic genetic mapping sequencing service for heartworm
• Simplified genome sequencing service for heartworm
• SNP detection trait localization service for heartworm

Service Details

Delivery content: experiment report.
Test fee: please get it through online inquiry.

Service Flow

1. Provide a preliminary project plan according to the customer's needs.
2. The company's technical team comprehensively assesses the feasibility of the project, works with the customer to determine the exact experimental project execution plan and gives the exact experimental price.
3. The customer signs the service agreement and prepays part of the fee, we do the initial preparation of the experiment and project prearrangement.
4. We formally start the experimental process, fully launch the experiment, and ensure the effective implementation of the project.
5. We communicate with the customer and give feedback on the latest progress of the experiment, and keep abreast of the latest developments of the experiment.
6. The client pays the remaining balance, we deliver the experimental results and provide after-sales service.

Our Advantages

• It can be widely used in heartworm mutation detection, genetic map construction, functional gene mining, population evolution and other research, which has significant scientific and industrial value.
• With rich experience in experiments and data analysis to provide better and more efficient services for customers.
• With rich experience in personalized analysis, we can choose the most suitable analysis software according to project needs, only to guarantee the most accurate results.
• Cost-effective, less time consuming and lower cost.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service