Parasites are single-celled or multicellular organisms that parasitize other organisms to obtain nutrition and survival. Parasitic infections often lead to serious health problems, including malaria, schistosomiasis, and leptospirosis, and pose a significant threat to global public health. Understanding parasite biology, pathogenesis and treatment is key to disease prevention, control, and treatment. Cytological techniques are one of the bases and tools for studying parasite biology and pathology. Currently, cytological techniques have been widely used in parasite-related research fields, including parasite morphological observation, apoptosis detection, immunohistochemical staining, in situ hybridization techniques, and parasite virulence detection.

Options for Cytological Technical Services for Parasite Research

Ace Therapeutics is a professional biotechnology services company dedicated to providing high-quality and reliable cytology technology services for parasite research to customers worldwide. With an experienced technical team and advanced experimental equipment, we can provide customers with a full range of technical support in experimental design, sample preparation, data analysis, and interpretation.

We offer a variety of parasite cytology technical services, including but not limited to the following:

• Parasitic cell culture services

Provide routine culture, passaging, and lyophilization services.

Optimize culture conditions to improve the survival and proliferation of parasitic cells according to customer needs.

Services such as identification, purification, and amplification of parasitic cells.

• Parasitic cell apoptosis study service

Detection of apoptosis of parasitic cells by TUNEL, Annexin V/PI staining, etc.

Analyze apoptosis-related protein expression levels and signaling pathways of apoptotic pathways by Western blotting and real-time fluorescence quantitative PCR.

• Cell proliferation/survival analysis service of parasites

The effects of different drugs or other treatments on parasite cell proliferation and survival were evaluated using MTT, CCK-8, and flow cytometry.

Establish data such as proliferation curves and half-inhibitory concentration (IC50) to evaluate indicators of drug efficacy and toxicity.

• Cell cycle analysis service of parasites

To study the different cycle stages of parasite cells and their changes using methods such as fluorescent staining and flow cytometry.

Analyze the changes in the expression of genes and proteins related to the regulation of the cell cycle.

• Cytological analysis service of parasites

Morphological and structural analysis of parasite cells based on light microscopic examination, electron microscopic observation, and chromosome morphological analysis.

Parasite genome and chromosome characterization using techniques such as chromosome labeling and fluorescent probes.

• Modeling services

Establishing cellular models suitable for studying the nature of infection and immune response of specific parasites according to customer needs and parasite species.

Optimization and validation of parameters such as selection of suitable models, infection dose, and infection time.

• Parasite drug screening service

Establish high-throughput drug screening platforms for different parasites.

Screen potential antiparasitic drugs and evaluate their toxicity and mechanism of action.

• Parasite metabolism analysis service

Use metabolomics and proteomics to study the metabolic pathways of parasites and their regulatory mechanisms.

Establish network models based on metabolic pathways to analyze the relationship between parasite metabolism and pathogenesis.

• Other customized services

We provide customized technical services in parasite pathology, such as the detection and identification of specific parasites, drug screening and evaluation, and toxicological evaluation, according to the needs and research purposes of our clients.

Applications

Our cytology technical services cover a wide range of parasite types and application scenarios, including but not limited to

• Plasmodium detection and analysis
• Schistosoma virulence assessment and genomic analysis
• Leptospira morphology and antigen expression analysis
• Immunohistochemical staining and in situ hybridization for Toxoplasma
• Virulence and protein expression analysis of Grassworm
• Morphological and genomic analysis of fungal parasites (Microsporidia)
• Phage infection of Cryptosporidium and its mechanism
• Virulence assessment and metabolic regulation of Giardia
• Biomarker and apoptosis detection of Trichomonas
• Exposure assessment and prevention strategy of Campylobacter infection
• Immunofluorescence staining and virulence analysis of Histoplasma

Thank you very much for your interest and trust in Ace Therapeutics. Our services cover all aspects of parasitic cells, providing a one-stop solution for our clients and establishing a good reputation in the field of parasite research. If you have any needs or questions related to parasitic cytology technology, please feel free to consult our customer service team. We will be happy to provide you with professional, high-quality service and to respond to your inquiries as quickly as possible. We look forward to working with you!

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service