The life history of Trichomonas vaginalis is simple, with a trophozoite stage and no encysted stage. The trophozoites are mainly found in the female vagina, especially in the posterior fornix, and may occasionally invade the urethra. In males, the trophozoites are usually found in the urethra and prostate, and can also invade the testes, epididymis and subcircumcision. The worms reproduce by the longitudinal bifurcation method. The trophozoite is both the reproductive stage and the infective and pathogenic stage. The worm is transmitted in the population by direct or indirect contact. The source of infection is the trichomonas patient and the carrier, mainly through direct sexual intercourse, but also indirectly through public baths, swimming pools, bidets, etc.
Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Trichomonas vaginalis. This provides a good model for the morphology, life history and especially the molecular biology of Trichomonas vaginalis and the study of Vaginitis.
We can construct a Trichomonas vaginalis model for you in rabbits, it can be used for scientific research and drug research of Vaginitis. If you want to know more, you are welcome to consult us.
Model animals: female rabbits that have given birth more than 2 times, weighing 1.5-2 kg, in good health and free of disease.
Source of Trichomonas vaginalis: obtained by culturing the vaginal secretions of patients.
Reproduction method: the Trichomonas vaginalis suspension obtained by culture was inoculated several times in the vagina of rabbits.
Model characteristics: localized secretion was increased and frothy, and the pH of the secretion was > 5.0. Live Trichomonas vaginalis was detected in the vaginal discharge (50 high magnification fields were observed) and persisted for more than 10 d. Pathological section shows a small number of eosinophils in the mucosal layer.
Applications: Its virulence and invasiveness as well as symptomatic manifestations vary depending on the strain and the physiological condition of the host organism. This model animal can be used for drug development and validation for the treatment of trichomoniasis.
Delivery content: experiment report and Trichomonas vaginalis animal model
Test fee: please get it through online inquiry.
Ace Therapeutics is a contract service provider focused on parasitology research, providing innovative solutions and technologies for parasite detection, genetic engineering, and drug development. We support global research institutes, universities, and pharmaceutical companies in advancing their research goals.