Trichinellosis is a human-animal parasitic disease, and humans, pigs, rats, cats, dogs and many wild animals can be hosts for this worm. Adult and larvae of Trichinella parasitise a single host, with adults in the small intestine and larvae in the rhabdomyocytes. After the muscle containing the cyst is ingested by a suitable host, the larvae develop further, mature and reproduce in the host's intestine. Trichinella causes a range of damage to the host during development, migration and parasitism.

The mucous membrane of the small intestine becomes congested and oedematous as a result of larval infestation, and infected individuals experience abdominal pain, diarrhoea, nausea and vomiting. The larvae enter the circulation and cause an allogeneic protein response, with persistent high fever, urticaria, maculopapular rash, eyelid and facial swelling in infected individuals.

Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Trichinella spiralis disease, aiming to facilitate in-depth investigation of biological challenges such as pathogenesis, epidemiological patterns, drug development, and efficacy evaluation of this disease.

Customization Service Options for Animal Models of Trichinella spiralis Infection

We can set up a Trichinella spiralis disease model for you in long-clawed gerbil or mice, it can be used for scientific research and drug research of Trichoderma. If you want to know more, you are welcome to consult us.

The long-clawed gerbil (Meriones unguiculatus) is ideal for establishing Trichinellosis animal models for parasitological and pharmaceutical studies, while the mouse is more suitable for trichinella conservation.

• Trichinellosis model in long-clawed gerbil (Meriones unguiculatus)

Long-clawed gerbils weighing 45-61 g and aged 9-12 weeks were selected.
Muscle of the preserved hosts containing Trichinella larvae was taken for compression counting.
Feeding 80 strips/each to long-clawed gerbils.

• Trichinellosis model in mice

This model is very similar to the time of onset and clinical manifestations of the larval migratory stage and adult cyst stage after human infection by Trichinella spiralis.

Service Details

Delivery content: experiment report and Trichinella spiralis disease animal model
Test fee: please get it through online inquiry

Service Flow

1. Communicate your project requirements with us via online inquiry or telephone.
2. Communicate the requirements (Number, degree of infection, etc.) of Trichinella spiralis disease animal model customization, sign the contract and pay the deposit.
3. (Optional) Fill out the sample order and send the samples.
4. Develop Trichinella spiralis disease animal model and prepare project experiment report.
5. Delivery of report and model.

Our Advantages

• We offer 2 murine species of Trichinella disease models, it can be used for scientific research and drug research of Trichoderma. If you have special needs, please consult us for customization.
• Our professional technicians have extensive experience in parasite animal model development.
• Advanced technology platform, scientific management system, and standard R&D procedures.
• In addition to Trichinella spiralis animal model customization service, we also provide Trichinella spiralis identification (stool tests, intradermal tests, latex agglutination tests, complement binding tests, convective immunoelectrophoresis, indirect immunofluorescence antibody tests, ELISA tests, etc.) and in vitro culture services.
• The project cycle time is short and the price is competitive.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service