Schistosoma haematobium is a human-animal interchangeable parasite. It has a wide variety of reservoir hosts, including cattle, pigs, dogs, sheep, horses, cats and rodents, and more than 30 other animals.

Schistosoma japonicum is parasitic in the portal vein system of humans or other mammals, mainly in the inferior mesenteric vein, where females lay eggs in the small veins of the intestinal wall and metaplasia occurs around the eggs. The eggs fall into the intestinal cavity from the ulcer of the intestinal wall and are excreted in the feces, where they hatch in the water as capillaries and invade the nail snail. Then, after the mother larva, daughter larva and caecal larva, the caecal larva escapes from the snail body and invades the body through the skin. The eggs, which are transported to the liver with the portal blood flow, cause metaplasia along the interlobular vein, resulting in cirrhosis of the liver. The mode of infection is closely related to the way of life and production of the person.

Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Schistosoma japonicum disease. This provides a good model for Schistosoma japonicum morphology, life history and especially the molecular biology provided a good model.

Customization Service Options for Animal Models of Schistosoma japonicum Infection

We can set up a Schistosoma japonicum disease model for you in rabbit or mouse, it can be used for scientific research and drug research of Schistosoma japonicum. If you want to know more, you are welcome to consult us.

• Natural infection model of Schistosoma japonicum (liver and spleen model)
• Lung egg granuloma model of Schistosoma japonicum (lung model)
• Liver egg granuloma model of Schistosoma japonicum (liver model)

Service Details

Model animal selection: rabbit or mouse
Source of parasites: escaped caecal larvae from positive nail snails
Method: infiltration abdominal method, intraperitoneal injection method
Delivery content: experiment report and Schistosoma japonicum disease animal model
Test fee: please get it through online inquiry.

Service Flow

1. Communicate your project requirements with us via online inquiry or telephone.
2. Communicate the requirements (Number, degree of infection, etc.) of Schistosoma japonicum disease animal model customization, sign the contract and pay the deposit.
3. Fill out the sample order and send the samples (optional).
4. Develop Schistosoma japonicum disease animal model and prepare project experiment report.
5. Delivery of report and animal model.

Our Advantages

• We provide models for 2 animals (rabbit and mouse) and 3 sites (natural infection model (liver and spleen model), lung worm egg granuloma model (lung model) and liver worm egg granuloma model (liver model)). it can be used for scientific research and drug research of Schistosoma japonicum. If you have special needs, please consult us for customization.
• Our professional technicians have extensive experience in parasite animal model development.
• Advanced technology platform, scientific management system, and standard R&D procedures.
• In addition to Schistosoma japonicum animal model customization service, we also provide Schistosoma japonicum identification (Direct smear test, capillary incubation method, quantitative transparency method, rectal mucosal biopsy test, intradermal test (IDT), circunoval precipitin test (COPT), indirect haemagglutination test (IHA), enzyme- linked immunosorbent assay (ELISA), immunoenzymic staining test (IEST), indirect fluorescent antibody test (IFAT), latex agglutination test (LA), enzyme-labeled antigen convective immunoelectrophoresis (ELACIE), etc.) and in vitro culture services.
• The project cycle time is short and the price is competitive.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service