Hydatidosis (hydatid disease), also known as echinococcosis, is a disease caused by the infection of humans with the larvae of Echinococcus granulosus. It is a zoonotic disease. Dogs are the final hosts, sheep and cattle are the intermediate hosts; humans become the intermediate hosts by accidentally ingesting the eggs and suffer from encystment disease. The eggs and nodules excreted in the feces can contaminate pastures, barns, hides, vegetables, soil, and water sources. When the eggs are swallowed by livestock (sheep, cattle) or people, the six hook larvae in the eggs hatch in the duodenum and burrow into the intestinal wall and enter the liver, lungs and other organs through the portal system, developing into encysted (echinococcal) larvae after about 5 months. If the animal's capsule is swallowed by a dog, its head segment grows into an adult worm in the dog's small intestine after 3 to 10 weeks. The adult worms are parasitized in the upper part of the small intestine (jejunum) of dogs and are fixed to the intestinal mucosa by parietal hooks and suckers, which do not cause symptoms in the host. In general, the course of cysticercosis is slow, with an incubation period of 1 to 30 years, and most patients often have no obvious symptoms. Clinically, echinococcosis is named according to the organ in which it is found, such as hepatocystosis, pulmonary encysticercosis, cerebral encysticercosis, osteocystosis, ocular encysticercosis, and others.

Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Hydatidosis. This provides a good model for the morphology, life history and especially the molecular biology of Hydatidosis.

Customization Service Options for Animal Models of Hydatid Disease

We can set up a Hydatidosis disease model for you in mice, it can be used for scientific research and drug research of Hydatidosis. If you want to know more, you are welcome to consult us.

• Mouse model of Hydatidosis

Experimental secondary infection animal model
Homozygous sequential transmission animal model
Allogeneic multiple transplantation animal model

Model animals: mice, generally pure-line mice or nude mice are preferred, and young mice are more sensitive.
Inoculation materials: The eggs, protoplasts and hair capsules of Echinococcus granulosus were used as infection materials.
Routes of inoculation: commonly used are transoral infection, subcutaneous injection, intraperitoneal injection and intraperitoneal transplantation.

Service Details

Delivery content: experiment report and Hydatidosis animal model
Test fee: please get it through online inquiry.

Service Flow

1. Communicate your project requirements with us via online inquiry or telephone.
2. Communicate the requirements (Number, degree of infection, etc.) of Hydatidosis animal model customization, sign the contract and pay the deposit.
3. Fill out the sample order and send the samples (optional).
4. Construct Hydatidosis animal model and prepare project experiment report.
5. Delivery of report and animal model.

Our Advantages

• We offer mouse and rat models of Hydatidosis that can be used for scientific research and drug research of Hydatidosis. If you have special needs, please consult us for customization.
• Our professional technicians have extensive experience in parasite animal model development.
• Advanced technology platform, scientific management system, and standard R&D procedures.
• In addition to Hydatidosis animal model customization service, we also provide Hydatidosis identification (Intradermal test, ELISA test, hemagglutination test, indirect immunofluorescence test, etc.) and in vitro culture services.
• The project cycle time is short and the price is competitive.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service