Encephalitozoon cuniculi is a specialized intracellular parasite found mainly in the cells of the brain, kidney, ascites macrophages, liver, spleen and other tissues and organs of rabbits, mice, rats, pigs, dogs, sheep and monkeys. Encephalitozoonosis is a chronic, cryptogenic protozoan disease caused by Encephalitozoon cuniculi. The worm mainly attacks brain tissue and kidneys, and the lesions are characterised by granulomatous encephalitis and granulomatous nephritis. The lesions are characterised by granulomatous encephalitis and granulomatous nephritis. The worms accumulate in mounds in the centre of the necrosis and the necrotic area is surrounded by an infiltration of lymphocytes, plasma cells, microglia and epithelial cells; sometimes there is an infiltration of macrophages and a vascular sheath formed by aggregations of lymphocytes and plasma cells around the vessels. Symptoms of encephalitis and nephritis are sometimes seen.

Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services forEncephalitozoon cuniculi. This provides a good model for the morphology, life history and especially the molecular biology of Encephalitozoon cuniculi.

Customization Service Options for Animal Models of Encephalitozoon cuniculi Infection

We can establish an Encephalitozoon cuniculi model for you in rabbits, puppies, guinea pigs, it can be used for scientific research and drug research of Encephalitozoonosis. If you want to know more, you are welcome to consult us.

• Rabbit model of Encephalitozoon cuniculi
• Puppy of Encephalitozoon cuniculi
• Guinea pig model of Encephalitozoon cuniculi

Model animals: rabbit, puppies, guinea pig and others.

Source of parasite: purified and collected Encephalitozoon cuniculi from the faeces of affected rabbits.

Reproduction method: oral, gavage or intranasal inoculation.

Model characteristics: the main organs of the infected animals have a large infiltration of inflammatory cells, and the cortical region of the kidney has a large number of granulomas centred on the worm and surrounded by lymphocytes, plasma cells and macrophages. Granulomatous lesions surrounded by lymphocytes, plasma cells, microglia and epithelial cells were seen in the brain parenchyma. The epithelium of the biliary tract is necrotic and detached.

Application: A powerful tool for the study of the pathogenesis and its specific control of Encephalitozoonosis.

Service Details

Delivery content: experiment report and Encephalitozoon cuniculi animal model
Test fee: please get it through online inquiry.

Service Flow

1. Communicate your requirements with us via online inquiry or telephone.
2. Communicate the requirements (Model animals, number, degree of infection, etc.) of Encephalitozoon cuniculi animal model customization, sign the contract and pay the deposit.
3. Fill out the sample order and send the samples (optional).
4. Establish Encephalitozoon cuniculi animal model and prepare experiment report.
5. Delivery of report and animal model.

Our Advantages

• We offer rat models of Encephalitozoon cuniculi that can be used for scientific research and drug research ofEncephalitozoon cuniculi. If you have special needs, please consult us for customization.
• Our professional technicians have extensive experience in parasite animal model development.
• Advanced technology platform, scientific management system, and standard R&D procedures.
• In addition to Encephalitozoon cuniculi animal model customization service, we also provide Encephalitozoon cuniculi identification services (Urine testing, intradermal testing, Gram stain/Typanlane stain, tissue sectioning, etc.).
• The project cycle time is short and the price is competitive.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service