Cryptosporidium (CPS) is an important opportunistic pathogen causing diarrhea in humans and animals and is widely found in many vertebrates. Cryptosporidium has a life history with five developmental stages: trophozoite, schizonts, gametophyte, conidia, and oocyst, of which the oocyst is the infective stage.

Cryptosporidiosis is a human-animal commensal protozoan disease caused by Cryptosporidium that has a worldwide distribution and can cause fatal diarrhea in immunodeficient or immunosuppressed individuals. The disease poses a serious risk to human health and animal production, and is one of the causes of death in human AIDS patients.

To date, many questions remain to be addressed in the study of the biological characteristics and pathogenesis of Cryptosporidium, and there are no specific drugs available for treatment. Therefore, it is necessary to establish a stable, reliable and convenient in vitro culture system or animal model.

Ace Therapeutics specializes in parasitology and has established a technical platform for the development of animal models of parasitic diseases, aiming to provide development and customization services for various animal models of parasitic diseases for clients worldwide. We provide animal model development services for Cryptosporidium disease. It provides a good basis for the growth and development process, immunology, vaccine research, drug screening and efficacy assessment, and oocyst inactivation techniques of Cryptosporidium.

Customization Service Options for Animal Models of Cryptosporidium Infection

We can set up a Cryptosporidium disease model for you in golden hamster, healthy KM mice or others, it can be used for scientific research and drug research of Cryptosporidium. If you want to know more, you are welcome to consult us.

• Golden hamster model of Cryptosporidium
• Healthy KM mice model of Cryptosporidium

Service Details

Model animal selection: golden hamster, healthy KM mice or others
Source of Cryptosporidium: human, porcine and sheep origin and others,
Other key reagents: dexamethasone, gentamicin and others.
Method options: Cryptosporidium oocysts gavage in mice, Cryptosporidium infected intestinal xenografts and others.
Delivery content: experiment report and Cryptosporidium disease animal model.
Test fee: please get it through online inquiry.

Service Flow

1. Communicate your project requirements with us via online inquiry or telephone.
2. Communicate the requirements (Number, degree of infection, etc.) of Cryptosporidium disease animal model customization, sign the contract and pay the deposit.
3. Fill out the sample order and send the samples (optional).
4. Develop Cryptosporidium disease animal model and prepare project experiment report.
5. Delivery of report and animal model.

Our Advantages

• We offer 2 murine species of Cryptosporidium disease models, it can be used for scientific research and drug research of Cryptosporidium. If you have special needs, please consult us for customization.
• Our professional technicians have extensive experience in parasite animal model development.
• Advanced technology platform, scientific management system, and standard R&D procedures.
• In addition to Cryptosporidium animal model customization service, we also provide Cryptosporidium identification (Direct smear staining of stool (watery or paste-like stool is preferred), parenteral biopsy, bile/sputum/bronchial lavage staining test, PCR and DNA probe test, ELISA test, etc.) and in vitro culture services.
• The project cycle time is short and the price is competitive.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service