Eimeria is a group of intracellular parasitic protozoa that are found in livestock, poultry and other animals. Its development can be divided into 3 stages: asexual reproduction, sexual reproduction and spore reproduction. Eimeria can cause huge economic losses to livestock and poultry breeding. Eimeria is also an important model organism for studying the biology and immunological characteristics of Eimeria. In recent years, with the rapid development of molecular biology, there has been a great breakthrough in the research of reverse genetic manipulation techniques such as transient transfection and screening of Eimeria. Meanwhile, the CRISPR/Cas9 system for gene editing of Eimeria crassa will also facilitate the study of the gene function of Eimeria crassa.

Ace Therapeutics, as a genome editing service provider, is focused on leveraging CRISPR/Cas9 technology and high-throughput screening to advance basic research and the pharmaceutical industry. We can provide CRISPR/Cas9 gene editing services for Eimeria coccinea to lay the foundation for in-depth elucidation of mechanistic studies.

CRISPR/Cas9 Genome Editing Service for Eimeria

We have a technical team with rich experience in CRISPR gene editing, and we can now realize one-stop service including gRNA design, CRISPR/Cas9 vector construction, transfection, and identification. After the service is completed, we will deliver you CRISPR/Cas9 gene editing products and detailed identification reports. If you want to know more, you are welcome to consult us.

• gRNA synthesis service
• CRISPR/Cas9 vector construction
• Cas9 vector activity validation
• CRISPR knockout cell line construction
• CRISPR knock-in cell line construction

Customers need to provide

• Eimeria coccidia strain
• Target gene related information
  1) Knockout: ID of knockout gene, lethality of pre-knockout gene
  2) Knock-in: sequence of knock-in DNA, knock-in site
  3) Point mutation: point mutation location and base change

Service Details

Delivery content: experiment report, gene editing monoclonal cell lines, Eimeria or Eimeria animal models that edited by CRISPR/Cas9 technology
Test fee: please get it through online inquiry.

Service Flow

1. The client sends the experimental plan, such as knockout cells, knockout target genes.
2. Program evaluation and quotation, communication and determination of program details. Sign the contract and pay the deposit.
3. Establish the needed Eimeria CRISPR/Cas9 system and prepare experiment report.
4. Delivery of report and products edited by CRISPR/Cas9 technology.

Our Advantages

• Authoritative detection methods and standardized service process.
• We have a strong technical support team and can provide free professional technical support for our customers.
• Gene editing is simple to perform and more precise in targeting.
• We can achieve knockdown of a single locus or multiple loci of target genes at the same time.
• We can also knock out multiple target genes at the same time.
• Short experimental cycle time and low price.

• Parasitology discovery and pre-research service
• Parasitology metabolism research service
• Parasitology target and structure function research
• Parasitology effectiveness evaluation service
• Parasitology safety evaluation service
• Parasitology pharmacological research service